Antonio Gates will play though is still coming back from injury, will still play well.
LB Tully Banta-Cain, QB Alex Smith, CB Marcus Hudson, CB Tarell Brown, CB Reggie Smith, C Cody Wallace, G Chilo Rachal, and LB Ahmad Brooks are all inactive for Week 1.
LT Marcus McNeill, C Justin Hardwick, QB Charlie Whitehurst, CB DeJuan Tribble, LB Anthony Waters, WR Buster Davis, TE Kris Wilson and DT Brandon McKinney are inactive for Week 1 against the Panthers.
QB Matt Moore, WR Ryne Robinson, CB C.J. Wilson, LB James Anderson, LB Donte Curry, G Mackenzy Bernadeau, DE Hilee Taylor and T Frank Omiyale are all inactive for Week 1 against the Chargers.
QB Brian St. Pierre, RB J.J. Arrington, T Brandon Keith, DT Alan Branch, TE Jerame Tuman, and DT Gabe Watson.
CB Terence Newman, G Kyle Kosier, G Montrae Holland, WR Sam Hurd, WR Miles Austin, DB Courtney Brown, and OLB Anthony Spencer are inactive for Week 1.
KR Joshua Cribbs, FS Brodney Pool, OL Ryan Tucker, G Rex Hadnot, TE Martin Rucker, LB Kris Griffin, NT Athyba Rubin, and QB Ken Dorsey.